Estimation of Skeletal Muscle Interstitial Adenosine During Forearm Dynamic Exercise in Humans
نویسندگان
چکیده
منابع مشابه
Estimation of skeletal muscle interstitial adenosine during forearm dynamic exercise in humans.
It has been proposed that adenosine is a metabolic signal that triggers activation of muscle afferents involved in the exercise pressor reflex. Furthermore, exogenous adenosine induces sympathetic activation that mimics the exercise pressor reflex, and blockade of adenosine receptors inhibits sympathetic activation induced by exercise. Thus, we hypothesize that adenosine is released locally by ...
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BACKGROUND Adenosine is a potent vasodilator that has been shown to increase in cardiac tissue in response to hypoxia. However, peripheral vasodilatation also occurs during hypoxia, and the vasoactive substance(s) responsible for skeletal muscle vasodilation have not yet been completely identified. Therefore, the purpose of this study was to measure and quantify skeletal muscle interstitial ade...
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Evidence from both animal and human studies suggests that adenosine plays a role in the regulation of exercise hyperemia in skeletal muscle. We tested whether adenosine also plays a role in the regulation of blood flow (BF) distribution and heterogeneity among and within quadriceps femoris (QF) muscles during exercise, measured using positron emission tomography. In six healthy young women, BF ...
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Fat and carbohydrate are the major energy substrates during aerobic exercise in well-fed humans. The regulation of fat metabolism during exercise has not been as thoroughly studied as carbohydrate metabolism, especially in human skeletal muscle. Traditionally, it was believed that the regulation of skeletal muscle fat metabolism was mainly at the level of the delivery of free fatty acids to the...
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Juel, C., H. Pilegaard, J. J. Nielsen, and J. Bangsbo. Interstitial K1 in human skeletal muscle during and after dynamic graded exercise determined by microdialysis. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278: R400– R406, 2000.—Interstitial K1 concentrations were measured during one-legged knee-extensor exercise by use of microdialysis with probes inserted in the vastus lateralis...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2000
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.35.5.1124